Most Cardiovascular Drugs Safe in Pregnancy

Most Cardiovascular Drugs Safe in Pregnancy

Most drugs used to treat various cardiovascular conditions are safe to use in pregnancy, according to a new analysis.

Researchers examined study data, guidelines and recommendations regarding the use of cardiovascular drugs during pregnancy. These include medications for irregular heartbeat (antiarrhythmics), hypertension drugs, heart failure drugs, statins and blood thinners (anticoagulants).

In their review, published in the Journal of the American College of Cardiology, the researchers note that precautions should be taken if a pregnant mother is on one of the medications.

“The lowest effective dose should be used. The woman should be counseled on risks and benefits, and provided current data, acknowledging limitations…. Maternal fetal medicine specialists should be consulted to assist in medication management during pregnancy, and the
pediatrician postpartum during lactation.”

Although the majority of the drugs are safe, the researchers caution that most of the drugs will enter breast milk, which could impact a newborn baby.

Some of the drugs that should not be used during pregnancy, according to the review, include the following: amiodarone, atenolol, angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers, statins, and direct oral anticoagulants (DOACs) such as Eliquis (apixaban), Pradaxa (dabigatran) and Xarelto (rivaroxaban).


Jonathan Block

Jonathan Block

Jonathan Block is an associate editor at BioCentury, which provides news and information about the biotechnology and pharmaceutical industries. Prior to joining BioCentury in 2019, Jonathan worked for MedShadow as content editor. He has been an editor and writer for multiple pharmaceutical, health and medical publications, including The Pink Sheet, Modern Healthcare, Health Plan Week and Psychiatry Advisor. He holds a BA from Tufts University and is earning an MPH with a focus on health policy from the CUNY Graduate School of Public Health & Health Policy.


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